If you are having issues with the RealSimGear plugin not finding the RealSimGear hardware, and you are also running AirManager, please check the steps below.
By default the AirManager application with try to automatically connect to all Arduino devices. You can disable this by un-checking the option within the AirManager settings.
Next, start X-Plane first, load the aircraft and check that the RealSimGear plugin has found all the devices. Now start the AirManager software.